Our Resource Page is evolving into a comprehensive knowledge center aligned with a more proactive, root-cause approach to bone health. Here you’ll find physician resources, exercise protocols, scientific research, educational videos, and blogs — with new content added along the way.
Resources
Proposed practice parameters for the performance of radiofrequency echographic multispectrometry (REMS) evaluations
Proposes standardized clinical guidelines for using radiofrequency echographic multispectrometry (REMS), a radiation-free ultrasound technology that can assess both bone mineral density and bone quality with accuracy comparable to DXA. Argues that REMS may improve fracture risk prediction and overcome key limitations of existing methods, especially in patients where DXA is less reliable (e.g., deformities, implants, or pregnancy). Overall, provides a framework to ensure consistent, accurate REMS use in clinical practice, particularly for osteoporosis assessment and orthopedic decision-making.
Dual-energy X-ray absorptiometry (DXA) to measure bone mineral density (BMD) for diagnosis of osteoporosis - experimental data from artificial vertebrae confirms significant dependence on bone size
This study demonstrates that DXA-measured bone mineral density is strongly dependent on bone size, meaning larger bones appear denser even when true density is the same. Using controlled artificial vertebrae, the authors confirm this effect quantitatively and show it can lead to potential misdiagnosis of osteoporosis.
Radiofrequency echographic multi spectrometry (REMS) in the diagnosis and management of osteoporosis: state of the art
This paper describes REMS as a portable, radiation-free ultrasound technology that measures bone mineral density and bone quality, showing strong agreement with DXA while also enabling fracture risk prediction through a “Fragility Score.” It highlights advantages over DXA, including use in sensitive or hard-to-scan populations (e.g., pregnancy, frail patients) and improved accuracy in the presence of artifacts. Overall, the evidence supports REMS as a reliable, accessible alternative or complement to DXA for osteoporosis diagnosis, monitoring, and fracture risk assessment.
Fragility Score: a REMS‑based indicator for the prediction of incident fragility fractures at 5 years
This study evaluates the REMS-derived Fragility Score (FS), a measure of bone quality independent of bone mineral density (BMD), for predicting incident fragility fractures over 5 years in nearly 2,000 patients. Overall, FS is presented as a reliable and superior tool for short-term fracture risk prediction, improving early identification and prevention of osteoporosis-related fractures.